Types of suppositories bases

Genel admin

Traditionally cylindrical in shape, suppositories can be classified into two base types: lipophilic and hydrophilic. Lipophilic suppositories are primarily fat- or wax-based and melt at human body temperature. Hydrophilic suppositories are polymer or glycerin based and require fluids to dissolve.Mordad 30, 1396 AP

What are the three types of suppository bases?

Suppository Bases

  • Fatty suppository bases.
  • Hydrophilic suppository base. Water-soluble/ water miscible bases. Emulsifying base.

What are the suppository bases?

Suppository bases usually used are theobroma oil, glycerinated gelatin, hydrogenated vegetable oils, mixtures of polyethylene glycols of various molecular weights, and fatty acid esters of polyethylene glycol.

What are the types of suppositories?

There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum, vaginal suppositories into the vagina, and urethral suppositories into the urethra of a male.

Which is most commonly used suppository base?

The most frequently used suppository bases, especially: 1) cocoa butter. 2) hydrogenated fatty acids of vegetable oils, such as palm kernel oil and cottonseed oil. 3) compounds consisting of glycerides of higher- molecular-weight fatty acids, such as glyceryl monostearate and glyceryl monopalmitate.

Which suppository base is more preferable?

β form The β form, which is the most stable, is preferable for suppositories. Cocoa butter will melt to form a nonviscous, bland oil. Because it is immiscible with body fluids, it may leak from the body orifice.

What are suppositories discuss the various types of bases and methods of preparation of suppositories?

Suppositories are prepared by rolling (hand-shaping), molding (fusion), and cold compression method.

What are ointment bases?

There are three major types of ointment bases: oleaginous (greasy) bases, which are water repellent; water-absorbing bases, which are greasy but allow absorption of water, and water-miscible bases (vanishing creams or water-soluble bases).